Abstract
The objectives of this study were to reduce the corrosion rate and increase the cytocompatibility of AZ31 Mg alloy. Two coatings were considered. One coating contained MgO (MAO/AZ31). The other coating contained Cu2+ (Cu/MAO/AZ31), and it was produced on the AZ31 Mg alloy via microarc oxidation (MAO). Coating characterization was conducted using a set of methods, including scanning electron microscopy, energy-dispersive spectrometry, X-ray photoelectron spectroscopy, and X-ray diffraction. Corrosion properties were investigated through an electrochemical test, and a H2 evolution measurement. The AZ31 Mg alloy with the Cu2+-containing coating showed an improved and more stable corrosion resistance compared with the MgO-containing coating and AZ31 Mg alloy specimen. Cell morphology observation and cytotoxicity test via Cell Counting Kit-8 assay showed that the Cu2+-containing coating enhanced the proliferation of L-929 cells and did not induce a toxic effect, thus resulting in excellent cytocompatibility and biological activity. In summary, adding Cu ions to MAO coating improved the corrosion resistance and cytocompatibility of the coating.
Highlights
One of the most crucial topics in the biomaterial field is the development of degradable biomaterials [1,2,3,4]
The experimental study was divided into three groups: AZ31 Mg alloy specified as the blank group, MgO-containing microarc oxidation (MAO) coating sample specified as the control group, and
L-929 cells cells cultured cultured with extracts from
Summary
One of the most crucial topics in the biomaterial field is the development of degradable biomaterials [1,2,3,4]. Metallic biomaterials are widely used in dentistry, orthopedics, and cardiovascular medicine [4,5]. Given their biological stability and excellent mechanical and processing properties, metallic biomaterials play an important role in implant applications [6,7,8]. Implants are used to reconstruct a failed tissue; a traditional biomaterial frequently requires a second surgery for removal [2]. The skeletal anchorage in orthodontics, such as miniscrews and miniplates made of magnesium alloys, provides stable implant materials that degrade in vivo [9,10], eliminating the need for a second operation for implant removal and helping to overcome the limitations of conventional orthodontic techniques [11].
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