Abstract
Fabrication of electrospun chitosan nanofibers is still a controversial issue in publications. Although regarding the lots of reports, mixtures of chitosan with a hydrophilic synthetic polymer such as polyethylene oxide (PEO) have been electrospun successfully, abundance of partly contradictory protocols in which one variable has been surveyed in each study is unfortunately baffling. In the present study, influence of three considerable parameters including the average molecular weight of chitosan, chitosan solution concentration and the mass ratio of polyethylene oxide to chitosan at the mixtures on electrospinning possibility as well as the quality of as-spun fibers is investigated. Eventually, the necessities for obtaining the best results are introduced followed by further analysis of optimized nanofibers using atomic force microscopy. According to our results, the blend solutions prepared from the low molecular weight (LMW) chitosan and PEO are efficient for reproducible production of bead-free electrospun nanofibers even in low proportion of polyethylene oxide.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.