Abstract
A rise of uric acid concentration in serum after rapid infusion of fructose in human beings was described at the first time in 1967 and confirmed a short time later ( 4,12 ). Sorbitol causes a weaker effect than fructose. However after the intravenous application of xylitol a powerful effect on uric acid concentration in serum is found ( 5 ). In contrast to the glucose substitutes glucose itself causes no hyperuricaemia. Long lasting infusions and oral applications of fructose, sorbitol, and xylitol increase uric acid concentration in serum too ( 6 ).
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