Influence of B. bovis hairworms on biochemical parameters of blood of patients with bovicolosis of calves

Abstract

The purpose of the work was to identify the features of the pathological process and changes in the main indicators of blood of cattle for the damage by its hairworms B. bovis. Scientific researches were conducted in the conditions of the Ploskivske BPPZ of the Brovarsky District of the Kyiv Region and the Laboratory of Biochemical Research of the National Cancer Institute. To do this, two groups of young cattle, black-and-white breeds up to one year old with 7 heads in each, were created. The experimental group included calves spontaneously invasive with hairworms. The control group was free of animal parasites. For this, they were previously, in two months, subjected to two-fold treatment with Insecticide Tactics (MSD, the Netherlands). Selected animals on the principle of analogues. All calves were in the same sanitary and hygienic conditions and received the same feed according to the diet. It was found that the glucose content in a sick young bovine animal was 6.25% (P < 0.5) higher than that in calf-free calves. There was a probable difference in the level of urea in the blood of animals, where the average level in the infected calves was 12.69% (P < 0.001) higher than in the control animals. The tendency to decrease by 15.31% (P < 0.5) was found in the average values of serum creatinine in calves in sick animals compared with the group of animals that served as controls and were free from parasites. In blood serum, calves infected with hairworms was found a slightly higher (4.25%, P < 0.5) level of total bilirubin than those found free from parasites. Indicators of serum cholesterol levels in blood serum of experimental animals were within normal limits. However, it was significantly lower by 14.71% (P < 0.05) in animals affected by parasites. The albumin-globulin ratio in our studies in invasive calves was 9.8% (P < 0.01) higher than that of control animals. In experimental calves with clinical manifestations of bovycolous, the average index of alkaline phosphatase content was 17.58% (P < 0.5) lower than its mean value in blood serum free of invasion by parasites of animals. Thus, among the biochemical parameters of serum of blood of invasive calves, a probable increase in urea and albumin to globulin ratios and a decrease in cholesterol was observed, indicating a negative effect of the hairworms on the organism of animals.