Abstract
Purpose of the study: The effect of an antitoxicant from the flora of Azerbaijan on hemato-logical parameters during nickel intoxication against the background of experimental atheroscle-rosis was studied. Materials and methods: The studies were conducted on male rats, which, after modeling atherosclerosis, were exposed to nickel through drinking water for 60 days at a dose of 2 mg/kg. In the experimental group, after poisoning against the background of experimental atherosclero-sis, rats received an antitoxicant, which was added to drinking water at a dose of 8 mg/kg for a month. The obtained results: The results of the study showed that after nickel intoxication against the background of experimental atherosclerosis, there was a decrease in the number of most blood elements: mainly granulocytes, hemoglobin and the average hemoglobin content in eryth-rocytes. Only the platelet count continued to increase during all periods of the study. After using the herbal antitoxicant were detected an increase in the level of hemoglobin, the average hemo-globin content in erythrocytes and a decrease in platelet content. Results: The obtained data indicate the corrective effect of this plant complex on hematolog-ical disorders and the feasibility of its testing in the clinic of chronic nickel poisoning.
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