Abstract
Gallbladder cancer (GBC) is the 6th most common gastrointestinal malignancy and most common hepatobiliary malignancy representing 85-90% worldwide with an annual incident of 2/1,00,000 and marked 1 geographical and ethnic variability and known for late diagnosis and poor outcome. High rates of gallbladder carcinoma are seen in different parts of the world like South America (Chilli, Bolivia, and 2 Ecuador) as well as in some parts of India (specically in north IndiaUP, Bihar, Delhi, West Bengal, Assam, and Madhya Pradesh, mostly in Gangetic belt), Pakistan, Japan, and Korea. In north India, gallbladder cancer is 10 times more common in comparison to south India. R 3 Kanthan et al . (2015) divides the risk factor for GBC into four broad groups: i)Patient demography, ii) GB abnormalities, iii)patient exposure to a specic chemical, genetic and molecular factors, iv) Infection. This study says that not only gallbladder stones but also infection by some microbial agents like salmonella and helicobacter also having contributory risk factors
Published Version
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