Abstract

Background: Acne vulgaris of infants is a well-recognized medical and cosmetic problem as it may cause severe scarring of the face. Hence medical treatment is essentially needed. Objective: To record all patients with infantile acne vulgaris and to do full demographic and clinical evaluation. Patients and methods:This is case series clinical descriptive study with interventional therapeutic trial that included all patients with infantile acne vulgaris that were seen during the period from Jan 2021 – September 2021 years. All demographic and clinical features were recorded. The clinical scoring of acne severity was done as follow:mild when the rash was mainly comedones,moderate mainly papules and pustules and severe mainly nodules and scarring. Any triggering factors were recorded including hormonal changes. Therapy was started by giving topical 2% clindamycin twice a day and oral trimethoprim-sulfamethoxazole suspension one teaspoonful twice a day for 1-2 months. Results: This study included 28 patients with infantile acne, with 19(67.86%) males and 9(32.14%) females with male to female ratio;2.1. The age of patients ranged from 1-24 months, with a mean 14.6 ±6.1.The duration of rash was ranged from 4-8 weeks. The commonest sites affected were cheeks in 27(96.4%) cases, followed by forehead in 8 (28.6%), then chin in 6 (23.1%), and nose 6 (23.1%) of the cases. Scoring of severity of acne showed moderate in 13(46.4%), followed by mild in 9 (32.1%), and sever in 6 (21.4%). The response to treatment was complete clearance in 15(53.6%) and partial response in 13(46.4%) of the patients while no adverse effects were observed. Conclusions: Infantile acne is not uncommon disease among infants where medical therapy is essentially needed especially in severe cases as to prevent facial scarring. Early diagnosis and treatment with oral trimethoprim-sulfamethoxazole suspension and topical 2% clindamycin lotion is an effective mode of therapy.

Highlights

  • The historic term, “infantile acne” has been used to describe true comedonal and inflammatory acne vulgaris that generally begins after the neonatal period, usually between 4 months and 5 years of age

  • The treatment strategy for infantile acne is similar to treatment of acne at any age, with topical agents including retinoids and topical antibacterials

  • Because reducing or eliminating dairy intake appears beneficial for adolescents with moderate to severe acne, this approach may represent a good option for infantile acne

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Summary

Introduction

The historic term, “infantile acne” has been used to describe true comedonal and inflammatory acne vulgaris that generally begins after the neonatal period, usually between 4 months and 5 years of age. [9] The aim of the present study is the to record all patients with infantile acne vulgaris and to do full demographic and clinical evaluation with therapeutic trial. Patients and methods infantile acne in a 6-month-old infant who was This a case series clinical descriptive study with successfully treated with ketoconazole cream therapeutic trial that was carried out during the. In addition to closed and open comedones, infantile acne may be first evident with papules, pustules, severe nodules, and cysts with scarring potential. The clinical scoring of acne severity was done as follow: mild when the rash was mainly comedones,moderate mainly papules and pustules and severe mainly nodules and scarring. Therapy was started by giving topical 2% clindamycin twice a day and oral trimethoprim-sulfamethoxazole suspension one teaspoonful twice a day for 1-2 months

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