Abstract
Surface-enhanced Raman scattering (SERS) spectroscopy is now a well-established phenomenon, which has been thoroughly characterized in a variety of interfacial and colloidal environments. Although some quantitative aspects of the underlying enhancement mechanisms apparently remain unresolved, attention is now shifting towards application of SERS to explore phenomena of chemical, physical, biological and industrial significance. The goal of this review is to appreciate the industrial value of innovative SERS technique on the basis of our experience in development of new SERS-active substrates and in their biomedical and biotechnological applications. Examples of diverse SERS analytical applications as well as some very recent facilities, as SERS microprobe analysis, SERS fiber optics probes, FT-SERS spectroscopy, SERS detection for high-performance liquid chromatography, etc. , are also discussed.
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