Abstract
In the experiment on rats by means of flow DNA-cytometry the dynamics of the cell cycle dynamics and DNA fragmentation of the renal cortex cells of the only kidney remaining after nephrectomy in rats was studied. Increase of proliferation activity and renewal in the immediate postoperative period after nephrectomy were found, which explains the increase in the mass and volume of the kidney. Kidney hypertrophy after unilateral nephrectomy in rats is accompanied by activation of apoptosis in the kidney tissue, resulting in increase of DNA fragmentation in the renal tissue of one kidney in experimental animals. The peak of this activation was observed on the 7th day after nephrectomy. It is indicative of apoptosis activation under conditions of intensified proliferation.
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