Abstract

While Tanzania is among the high TB burden countries to reach the WHO's End TB 2030 milestones, 41% of the people estimated to have had TB in 2020 were not diagnosed and notified. As part of the response to close the TB treatment coverage gap, SHDEPHA+ Kahama conducted a TB REACH active case-finding (ACF) intervention among rural and mining communities in Northwest Tanzania to increase TB/HIV case notification from July 2017 to June 2020. The intervention successfully linked marginalized mining communities with integrated TB/HIV screening, diagnostic, and referral services, screening 144,707 people for TB of whom 24,200 were tested for TB and 4,478 were tested for HIV, diagnosing 1,499 people with TB and 1,273 people with HIV (including at least 154 people with TB/HIV coinfection). The intervention revealed that community-based ACF can ensure high rates of linkage to care among hard-to-reach populations for TB. Providing integrated TB and HIV screening and diagnostic services during evening hours (Moonlight Events) in and around mining settlements can yield a large number of people with undiagnosed TB and HIV. For TB, this is true not only amongst miners but also FSW living in the same communities, who appear to be at similar or equally high risk of infection. Local NGOs can help to bridge the TB treatment coverage gap and to improve TB and HIV health outcomes by linking these marginalized groups with public sector services. Capturing the number of referrals arriving at CTCs is an important next step to identify how well the integrated TB/HIV outreach services operate and how they can be strengthened.

Highlights

  • IntroductionDiagnosis and treatment of tuberculosis (TB) are vital components of the End TB Strategy target to reduce the number of TB deaths by 95% by 2035 from 2015 [1]

  • Our study showed a large drop-off in the link to human immunodeficiency virus (HIV) testing amongst those tested for TB, with HIV high-risk groups like artisanal small-scale miners (ASMs) and female sex workers (FSWs) even less likely to appear for HIV testing

  • Based on our study’s overlapping 95% confidence intervals for B+ TB prevalence rates and the same all forms TB prevalence estimate (3.0%), these findings suggest that burden among FSWs, who are not directly involved in mining may be similar to miners themselves and more importantly, is incredibly high

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Summary

Introduction

Diagnosis and treatment of tuberculosis (TB) are vital components of the End TB Strategy target to reduce the number of TB deaths by 95% by 2035 from 2015 [1]. An estimate of the proportion of people with TB who are detected and notified, is an important measure of access to TB diagnosis and care [2]. E World Health Organization (WHO) estimated Tanzania’s 2020 tuberculosis (TB) treatment coverage cases to be. Tanzania is designated as one of WHO’s 30 high burden countries for TB and TB/HIV, and Journal of Tropical Medicine despite its 2019 population of 58 million people, 5% of all people globally with TB/HIV live in the country [2]. E London School of Health and Tropical Medicine’s subnational burden estimation tool SUBSeT places regions in northwestern Tanzania among those with the lowest treatment coverage with various areas under 40% [6]. One of the potential reasons for low treatment coverage is the presence of several key populations for TB who tend to suffer from poor access to health services, stigma, and discrimination [7, 8]. Despite the presence of risk factors for TB, the TB prevalence among both risk groups remains unexplored

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