Abstract
Prof. Dr. Andre Keren ()) Center for Heart Failure and Heart Muscle Diseases Heart Institute Hadassah University Hospital Hadassah-Hebrew University Medical School Jerusalem 91120, Israel E-Mail: andrek@cc.huji.ac.il Hypertrophic cardiomyopathy (HCM), defined clinically by the presence of unexplained left ventricular hypertrophy [1], is the most common inherited cardiac disorder affecting one in 500 people [2, 3]. Approximately 25% of patients have left ventricular outflow obstruction at rest and 70% can develop outflow gradients during exercise [4]. The dynamic outflow obstruction is caused by the abnormal systolic contact between the hypertrophied basal interventricular septum and the anterior mitral leaflet
Published Version
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