Abstract
Plain Language SummaryChronic kidney disease (CKD) and heart failure (HF) are two conditions that are common, often coexist and cause higher rates of mortality. However, the effect of HF on the incidence of end-stage kidney disease (ESKD) is not well studied. This observational study aimed to understand the association between a specific type of HF, HF with reduced ejection fraction (HFrEF), and the incidence of ESKD. Our study showed that the presence of HFrEF in an individual with CKD was associated with a higher risk of ESKD. These findings were consistent after correcting for other related factors such as age, diabetes, and urinary protein by using two methods of propensity matching. These findings highlight the importance of using appropriate measures such as a multidisciplinary health care approach and utilising protective medications to delay the progression of CKD.
Published Version
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