Abstract
Impaired insight into illness is a common feature of schizophrenia that negatively contributes to clinical outcomes. Previous functional MRI studies suggest that impaired insight may be related to posterior parietal area (PPA) function. Arterial spin labeling (ASL) is a non-invasive brain imaging technique that provides an absolute measure of regional cerebral blood flow(rCBF). Little research has explored the relationship between rCBF and insight into illness in schizophrenia. We aimed to use pseudo-continuous ASL (pCASL) to examine the association between rCBF and impaired insight in patients with schizophrenia.
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