Abstract
Rapid tumor growth has been associated with markedly altered polyamine biosynthesis and accumulation (1), and an increase in the concentrations of plasma and urinary polyamines might provide an independent biochemical marker of disease activity and response to therapy (2)(3)(4)(5). However, because the components of urine and plasma show variations throughout the day and because these two specimens are rather inconvenient to obtain and handle, another noninvasive method for measuring polyamine concentrations was required. According to recent reports, hair fibers may be used to …
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