Abstract
We determined the intravitreous level of 8-hydroxydeoxyguanosine (8-OHdG) in diabetic retinopathy (DR) and analyzed the relation between oxidative stress and DR. Vitreous 8-OHdG concentration increased significantly in 18 patients (20 eyes) with DR compared with controls with macular disease. This result suggests that increased oxidative stress is involved in DR.
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