Abstract

Omics technologies and neovascular ocular disorders.

Highlights

  • Neoangiogenesis plays an important role [2], while various environmental and genetics factors are involved in their pathogenesis [2]

  • Inflammation has an important role in the development of proliferative diabetic retinopathy (PDR) as described in the paper by M

  • Several pathogenetic mechanisms have been implicated in the development of PDR such as alteration in retinal blood flow, hemostatic abnormalities, metabolic changes, increased oxidative stress, increased polyol and hexosamine pathway flux, activation of protein kinase C isoforms, and increased advanced glycation end-product formation, growth factors, and so forth

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Summary

Introduction

Neovascular ocular disorders such as diabetic retinopathy and neovascular age-related macular degeneration (neovascular AMD) are an important cause of blindness in the world [1]. Inflammation has an important role in the development of proliferative diabetic retinopathy (PDR) as described in the paper by M.

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