Abstract
PREECLAMPSA ANNA-KARIN WIKSTROM, MATTS OLOVSSON, Uppsala University, Women’s and Children’s health, Uppsala, Sweden OBJECTIVE: The antiangiogenic substance soluble VEGF receptor 1 (s-Flt1), has been suggested to be involved in the pathogenesis of preeclampsia (PE). Early onset PE is generally more aggressive in clinical practice than late onset PE, and shows a stronger association to impaired placentation. The aim of this study was to determine if the maternal s-Flt-1 levels are different in early compared to late onset disease. STUDY DESIGN: Serum samples were collected from two groups of cases:
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