Abstract
Lactating rats were fed an 8% protein-restricted diet (PR), a 23% protein diet (C), and an energy-restricted pair-fed to PR group (PF). Thyroxine (T 4) and triiodothyronine (T 3) concentrations were analyzed in milk and in the serum of mothers and pups on different days of lactation. Serum T 3 was always higher ( p < 0.01) in PR mothers, while T 4 was lower ( p < 0.05) on days 4 and 21. PR group showed higher T 3 ( p < 0.001) on days 4, 8, and 12, while PF showed higher T 3 in milk ( p < 0.05) on days 12 and 16. In PR pups serum T 3 was higher ( p < 0.05), while T 4 was lower on day 4 and both were lower ( p < 0.05) on day 12. In PF pups T 3 was lower ( p < 0.05) on day 21, and T 4 was lower ( p < 0.01) on day 12. These data suggest a higher transfer of T 3 for the PR pups that could be important for their nervous system development.
Published Version
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