Increase of drainage and immune functions of the lymph node as a result of phytostimulation in old age

Abstract

Background: The most priority in medicine is the problem of providing an immune protection and increase in nonspecific resistance of an organism at elderly and senility age. First of all, search of ways of control of functions of lymphatic system is necessary for counteraction to aging. It is possible to make it by means of lymphotropic technologies of preventive medicine if to consider the concept of the lymphatic region. Methods: In the experiment used 160 albino rats that were divided into groups of young and old animals. The mesenteric lymph node is chosen as a research object. We used the original herbal remedy (phytocomposition) to improve the function of the lymph node. We conducted a histologic research of mesenteric lymph nodes. We defined the content of trace elements (Mn, Fe, Cu, Zn, Se) in a mesenteric lymph node by means of the radiofluorescence analysis with use of the synchrotron radiation (RFA SI). Morphometric data processing was performed with licensed statistical software package StatPlus Pro 2009, AnalystSoft Inc. Results: Age-related changes in mesocolic lymph node reflect the general process of ageing. These changes of lymph node are associated with reduction of structural and functional compartments and with excessive manganese content and deficiency of trace elements (iron, zinc, and selenium). There is a decrease in drainage and immune function of lymph nodes in the elderly and senile age. We have realized the idea to control the lymphatic system functions using phytotherapy. Phytotherapy provides improved drainage and immune functions of the lymph node by increasing the size of functional compartments, intensification of cellular proliferation and mitigating the deficiency of the main trace elements. There is the formation of new lymphoid follicles after phytostimulation. Conclusion: Phytotherapy has a structural-modifying effect, which is important for improving the non-specific resistance of the body at the late stage of ontogenesis. This result is of practical importance for the optimization of endoecological rehabilitation.Key Words: Uterine fibroids, Menorrhagia, Pulmonary embolism, Deep venous thrombosis, Ovarian benign tumor.