Abstract
This chapter provides a basic overview of the multiple aspects and considerations that impact the proper conduct of regulatory toxicologic pathology studies. The chapter introduces the novice toxicologic pathologist to topics that include, but are not limited to, Good Laboratory Practices, animal welfare issues, necropsy processes, clinical chemistry data, organ weight data, tissue fixation, histology procedures, and Cause of Death documentation. The goal of the chapter is to enhance awareness of factors that influence study protocol development and interpretation of in-life, gross, and histomorphologic data. Regulatory topics are also briefly discussed.
Published Version
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