Abstract
Abstract We investigated the 1:1 molecular inclusion of three bioenergetically important tyrosine derivatives, e.g., dopamine hydrochloride, tyramine hydrochloride and (±)-epinephrine hydrochloride with cyclic oligosaccharide (α-cyclodextrin) in aqueous medium of various pH conditions (e.g., at pH = 7.4 and at pH = 9.0). Surface tension and specific conductivity measurements were used to explain the molecular ratio of inclusion complexes. Using Benesi–Hildebrand method with the help of UV–Vis spectroscopic inspection, apparent formation constants (K) and thermodynamic parameters for the inclusion have been determined. 1 H NMR study of α-cyclodextrin confirms the inclusion phenomenon. Hydrophobicity, H-bonding and pH of the medium play a significant role to validate the stability of the inclusion complexes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
