Abstract

Introduction: The incidence of malignancy in multinodular goitre has been found to vary from 4%-17%. Our aim is to know the incidence of malignancy in clinically benign multinodular goiter. Material and Methods:This retrospective, analytical study done in operated patients who are admitted for clinically benign multinodular goiter in Fr Muller medical college Hospital during 2012-2013 (2yrs).All the operated specimen sent for histopathological examination to rule out malignancy. Results: Among 182 operated specimen 15 (8.2%) contained malignant foci. Papillary carcinoma is the most common malignancy observed. Conclusion:The risk of malignancy in MNG should not tobe underestimated. Total/near total thyroidectomy is the preferred operation. All the operated specimen sent for histopathological examination to rule out malignancy.

Highlights

  • The incidence of carcinoma in multinodular goiter (MNG) has been found to vary from 4% to 17%

  • Our aim is to determine the incidence of malignancy in multinodular goiter by doing the histopathological examination of thyroidectomy specimens

  • The aim of the study is to carry out retrospective analysis of patients who have been operated for normal or hyper functioning MNG, in order to establish the incidence of the histopathologically documented carcinoma or of the occult carcinoma found only after a complete histopathological examination of the total/near total thyroidectomy specimen

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Summary

Introduction

The incidence of carcinoma in multinodular goiter (MNG) has been found to vary from 4% to 17%. Our aim is to determine the incidence of malignancy in multinodular goiter by doing the histopathological examination of thyroidectomy specimens. All the operated specimens were subjected to a histopathological examination to determine the incidence of malignancy. The incidence of carcinoma in multinodular goiters (MNG) has been found to vary from 4% to 17% 1. Ascertained risk factors are ionizing radiation, the presence of thyroid adenoma and multinodular goiter (MNG). The aim of the study is to carry out retrospective analysis of patients who have been operated for normal or hyper functioning MNG, in order to establish the incidence of the histopathologically documented carcinoma or of the occult carcinoma found only after a complete histopathological examination of the total/near total thyroidectomy specimen

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