Abstract

Incidence of Second Cancers in Thyroid Cancer Patients Treated with Radioactive Iodine Ablation: How High Is Really the Risk?

Highlights

  • Thyroid cancer is the most commonly diagnosed endocrine tumor and the incidence in thyroid cancer is rising throughout the world [1,2]

  • The relative risk of second primary malignancies in thyroid cancer survivors treated with radioactive iodine ablation (RIA) was significantly increased at 1.19 (95% confidence interval: 1.04-1.36) relative to thyroid cancer survivors not treated with RIA, using a minimum latency period of 2 to 3 years after thyroid cancer diagnosis

  • In summary, we have provided a short overview of the literature addressing the issue of the incidence of second tumors in differentiated thyroid cancer (DTC) patients in relation to RIA

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Summary

Introduction

Thyroid cancer is the most commonly diagnosed endocrine tumor and the incidence in thyroid cancer is rising throughout the world [1,2]. Because of the excellent prognosis of differentiated thyroid cancer (DTC) and the fact that radiation exposure represents a risk factor for many other cancers, in the last years there has been an exponential attention to the possible association between RIA and second malignancies in thyroid cancer patients [19].

Results
Conclusion

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