Incidence of retinopathy of prematurity in extremely premature infants.

Alparslan Şahin,Muhammed Şahin,Harun Yüksel,Şeyhmus Arı,Yasin Çınar,İhsan Çaça,Abdullah Kürşat Cingü,Fatih Mehmet Türkcü

doi:10.1155/2014/134347

Alparslan Şahin, Muhammed Şahin + Show 6 more

Open Access

https://doi.org/10.1155/2014/134347

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Journal: ISRN Pediatrics	Publication Date: Mar 9, 2014
Citations: 27	License type: CC BY 3.0

Affiliation: Dicle University

Abstract

Purpose. To investigate the incidence and the severity of retinopathy of prematurity (ROP) in extremely preterm infants born before 28 weeks of gestation in southeastern Turkey. Methods. A retrospective chart review was performed for infants born before 28 weeks of gestation. The following data were reviewed: gender, gestational age (GA), birth weight (BW), zone and stage of ROP, presence of plus disease, and treatment for ROP if needed. Infants were divided into 2 groups according to GA as follows: group 1 included infants of GAs 25 weeks and under; group 2 included infants of GAs less than 28 weeks and over 25 weeks. Results. The incidence of any ROP in the whole cohort, in group 1, and in group 2, was 66.0%, 95.5%, and 58.6%, respectively. Incidence of any ROP was significantly associated with BW and GA (P = 0.014 and P = 0.002, resp.). The overall incidence of type 1 ROP was 35.8% (59.1% in group 1 and 29.9% in group 2). Development of type 1 ROP was independently associated with GA. Conclusion. Any ROP was significantly associated with BW and GA. Extremely premature infants with lower GA were found to be more likely to develop type 1 ROP. BW cannot predict the development of type 1 ROP.

Highlights

Retinopathy of prematurity (ROP) is an important cause of vision loss in children, especially in extremely premature infants [1]
From September 2010 to August 2012, the medical records of 526 premature infants were reviewed in the Hospital of Dicle University, and 109 of them were eligible for the study. 22 of the premature infants were ≤25 weeks of gestational age (GA) and 87 of them were over 25 weeks of GA
The survival rate of extremely premature infants continuously increases as a consequence of the advancement of neonatal care [5]

Summary

Introduction

Retinopathy of prematurity (ROP) is an important cause of vision loss in children, especially in extremely premature infants [1]. The incidence of ROP is rising with the improvement of the survival rates of extremely premature infants [5, 6]. These infants are more tending to develop severe ROP and require treatment [7].

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Conclusion