Incidence and risk factors of retinopathy of premature and low birth weight infant

Abstract

Objective To investigate the incidence and risk factors of retinopathy in premature and low birth weight infants. Methods One hundred and twelve premature infants and low birth weight infants were selected from December 2013 to June 2016.We used the lens (28D) and indirect fundus lens combined with scleral compression device to examine the fundus of the study.We calculated retinopathy detection, and analyzed the correlation between the rate of neonatal body weight, gestational age and gender and pathogenesis of retinopathy, and other factors (apnea, premature rupture of membranes, blood transfusion, mechanical ventilation, multiple births, splits the palace production) and retinopathy rate correlation and retinopathy independent risk factors. Results Among the 112 cases of premature and low birth weight infants, there were 12 retinal diseases, and the incidence rate was 10.71% (12/112). There was significant difference in the incidence of neonatal body mass than 2 000 g, 1 500-2 000 g, and less than 1 500 g retinopathy (P 0.05). There were close correlation of the respiratory pause, mechanical ventilation with the incidence of retinopathy, and the differences were significant (P 0.05). The Logistic multiple regression analysis showed that the independent risk factors of retinopathy of premature and low birth weight infants included the apnea, mechanical ventilation, body weight, gestational age. Conclusions Apnea, mechanical ventilation, body weight, gestational age are independent risk factors for premature and low body weight infant retinopathy, clinicians should timely make intervention measures according to whether with such risk factors, reduce the incidence of retinopathy, and improve the prognosis. Key words: Premature infant; Low weight infant; Retinopathy; Risk factor