Abstract
Background Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum. The aim was to determine the incidence and clinicopathological characteristics of benign salivary gland neoplasms diagnosed between 2007 and 2016 in a single center located in northeastern Brazil. Material and Methods Records regarding sex, age, anatomical location, histopathological subtype and treatment were retrieved, and data were analyzed using the Stata/IC software (version 12.0). Results There were above 7,100 cases of neoplasms in the head and neck region, of which 403 corresponded to salivary gland neoplasms. Of these, 238 (59%) were benign, being pleomorphic adenoma (PA) the most frequent neoplasm (n=178; 74.8%), followed by Warthin's tumor (WT) (n=23; 9.7%). Overall, most cases occurred in females (n=136; 57.1%) and age ranged from 11 to 83 years. The parotid gland (n=188; 79%) was the most common anatomical site, and all patients were treated by surgical excision. Of the cases diagnosed as PA, malignant transformation to carcinoma ex-pleomorphic adenoma (CAEXPA) occurred in 7 (3.9%) cases. Conclusions The present study confirmed the clinical and demographic profile of benign salivary gland neoplasms, which contributes to the continuous knowledge of current data about these lesions. Key words:Salivary gland, benign neoplasms, epidemiology.
Highlights
Benign tumors of the salivary glands are a group of lesions with varied histopathological and clinical spectrum
Large series report that approximately 64-80% of primary neoplasms of epithelial origin occur in the parotid, 7-11% in the submandibular gland, less than 1% in the sublingual gland and 9-23% in minor salivary glands (2-8)
There were 238 cases of benign salivary gland neoplasm, which corresponded to 59% of all salivary gland neoplasms and 3.3% of the head and neck tumors
Summary
Approximately 230,635 lesions were diagnosed in the referred hospital. 7,100 were cases of head and neck neoplasms, of which (5.7%) were of salivary gland neoplasms. There were 238 cases of benign salivary gland neoplasm, which corresponded to 59% of all salivary gland neoplasms and 3.3% of the head and neck tumors. Most cases were diagnosed in females (n=136; 57.1%) and age varied between 11 and 83 years, with an average of 48 years-old (SD±16). PA was the most frequent neoplasm (n=178; 74.8%), followed by WT (n=23; 9.7%) (Table 1)
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