Inactivation and Degradation of Influenza A Virus on the Surface of Photoactive Self-Cleaning Cotton Fabric Functionalized with Nanocrystalline TiO2

Abstract

Chemical modification of cotton-rich fabrics with TiO2 nanoparticles results in photoactive self-cleaning textiles, which can provide, under UV or solar radiation, complete oxidation of low-molecular compounds, degradation of supramolecular structures, and inactivation of microorganisms due to the photocatalytic effect. In this paper, we describe, based on the example of influenza A (H1N1) virus, a photoinduced antiviral effect of cotton fabric functionalized with nanocrystalline TiO2. Fast inactivation of influenza virus occurs on the irradiated surface of photoactive fabric due to adsorption and photocatalytic degradation. The TiO2 component in the prepared fabric increases the adsorption effect compared to initial cotton due to a high specific area of TiO2 nanocrystallites. Long-term irradiation leads to destruction of all virion structures to the point of RNA molecules. In contrast to pristine cotton, no virus RNA is detected using the polymerase chain reaction (PCR) technique after long-term irradiation of photoactive fabric. The results of this study underline the potential of photoactive self-cleaning fabrics for application in air purification systems and personal protective clothes to provide permanent protection of people against harmful chemical and biological pollutants.