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PDF Availablehttps://doi.org/10.1128/jb.185.22.6728-6731.2003
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Cite Journal: Journal of Bacteriology |  Publication Date: Oct 31, 2003 |
 Citations: 7 |
Affiliation: University of Turku
The Bacillus subtilis PurR mediates adenine repression and guanosine induction of purA. PRPP inhibits binding of PurR to DNA in vitro. Mutations in the PRPP binding motif of PurR caused strong repression regardless of purine exclusions or additions, establishing the role of PRPP as regulator of PurR.
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