Abstract
A series of novel Ni free Zr-based bulk metallic glasses (BMGs) with composition of Zr48Cu45Al7 (Ag0), Zr48Cu42Al7Ag3 (Ag3), Zr48Cu37Al7Ag8 (Ag8) Zr48Cu33Al8Ag11 (Ag11) were fabricated by arc-melting/copper mold suction-casting under a purified argon atmosphere. The microstructure, hardness, hemocompatibility and cellular responses were investigated in this study. The results indicated that the Ni free Zr-based BMGs exhibited much higher Vickers hardness than that of pure Zr. The Ni free Zr-based BMGs possessed a lower hemolysis ratio than the safe value of 5% according to ISO 10993–4 and a significant lower number density of adhered platelets. MTT assay results revealed that the relative growth rate (RGR) values of the Ni free Zr-based BMG samples were Grade 1 according to ISO 10993–5:2009, which means that the BMG samples have good cell viability.
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