Abstract
Somite mesoderm from the anterior region of mouse embryos possessing fewer than 25 somites fails to produce cartilage or bone either in culture or on subsequent implantation into the anterior chamber of the eye. When combined in culture with pieces of spinal cord from the same stage embryos, however, the mesoderm differentiates cartilage nodules in culture and produces bone including hematopoietic tissue, adipose tissue and occasional lymphoid tissue on implantation into the eye.
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