Abstract
Dental erosion is considered one of the oral cavity diseases. Frequent intake of liquid oral medications can be an effective factor in tooth erosion. This study aimed to evaluate the effects of frequently prescribed pediatric drugs on the permanent dental enamel microhardness over a period of 14 days in vitro. In this study, 11 pediatric drugs with different active ingredients were used; the control group consisted of teeth immersed in distilled water. The immersion cycles were applied 3 times a day for 1 min. The measurements of the samples prepared were taken at 0 (baseline), 7 and 14 days after the immersion cycles using a Vickers hardness testing machine. The pH, titratable acidity (TA) and buffering capacity of the syrups were assessed. The measurements of the tooth samples that were immersed in drug solutions except Deltacortril® showed that there was a significant difference between days 0, 7 and 14. The microhardness values for the tooth samples that were immersed in the Deltacortril drug solution decreased, but no significant difference was found. There were no statistically significant differences between the day 0, 7 and 14 measurements in the control group. Commonly used and prescribed pediatric drugs pose a risk for tooth erosion. Pediatricians should be aware of the effects of prescription drugs on erosion, and stress the need for compliancy with oral hygiene procedures.
Highlights
Oral health is known to have a direct impact on the growth, development and general health of children
This study aimed to evaluate the effects of frequently prescribed pediatric drugs on the permanent dental enamel microhardness over a period of 14 days in vitro
The measurements of the tooth samples that were immersed in drug solutions except Deltacortril® showed that there was a significant difference between days 0, 7 and 14
Summary
Oral health is known to have a direct impact on the growth, development and general health of children. Dental erosion is considered one of the oral cavity diseases[1,2] and is defined as irreversible progressive loss of hard dental tissues by chemical dissolution without bacterial involvement.[3] It has been reported that when the pH of the oral environment reaches a critical cutoff value of 5.5, the demineralization of the enamel will occur.[4] The erosion begins with the softening of the enamel surface, mainly characterized by a reduction in microhardness.[5] This erosion is a multifactorial, irreversible process resulting from internal, external or idiopathic factors.[6] Intrinsic etiological factors, which are caused by the contact of dental tissue with stomach acids, include eating disorders, regurgitation and reflux[7]; acidic drugs, diet, environment, and behavioral factors are external etiological factors.[8,9,10,11,12]. Dental erosion is considered one of the oral cavity diseases. Frequent intake of liquid oral medications can be an effective factor in tooth erosion
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