Abstract

The present study is to evaluate the biopotency of Cordia dichotoma. The fruit extracts was examined for antioxidant, cytoprotective and antiulcer properties. Total polyphenolics content in Aqueous and methanolic extracts were found to be 5.81 and 3.56 Tannic acid equivalents (TAE) mg/g respectively. The phenolic contents were examined for radical scavenging activity by DPPH method. The antioxidant potential of these extracts was determined by reducing power assay and IC 50 was calculated. The cytoprotective studies were carried out using RBCs by biochemical and microscopic methods. Finally, antiulcer activity is evaluated by using H + K + -ATPase inhibition. During antiulcer studies the aqueous extract exhibited almost equal potential with respect to omeprezole (proton potassium ATPase inhibitor) drug. Whereas methanolic extract exhibited more potential than that of aqueous extract. The potentiality was based on IC 50 values.

Highlights

  • Child marriage, known as early marriage, is defined as “any marriage carried out below the age of 18 years, before the girl is physically, physiologically, and psychologically ready to shoulder the responsibilities of marriage and childbearing

  • The main objective of this study is to assess the prevalence of early marriage practice among female child from 2009 to 2013 in Sinane district northwest Ethiopia

  • The prevalence of early marriage practice is high in the study area

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Summary

Introduction

Known as early marriage, is defined as “any marriage carried out below the age of 18 years, before the girl is physically, physiologically, and psychologically ready to shoulder the responsibilities of marriage and childbearing. It has major consequences for public health, national security, social development, human rights, economic development and gender equality[1]. Girls are either seen as an economic burden or valued as capital for their exchange value in terms of goods, money or livestock that is for economic and social reasons, controlling girls‟

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