In Vitro Evaluation of Antioxidant, Antiglycation and Anti-Protein Denaturation Potentials of Indigenous Myanmar Medicinal Plant Extracts

Abstract

ABSTRACT The antioxidant, anti-glycation and anti-protein denaturation potential of test extracts were assessed by hemolysis, antioxidant, antiglycation, and anti-protein denaturation assays. The cytotoxic effect of the tested extracts ranged from 6.18 ± 0.15 to 29.33 ± 1.47%. The highest effect was noted in C. carandas, H. cannabinus, T. chebula and H. indicum in antioxidant assay. The phenolic content ranged from 84.73 to 238.23 mg GAE g−1 of extract and the flavonoid was 36.05 to 184.26 mgRE g−1 of extracts. Antiglycation activity exhibited in M. longifolia, T. chebula, H. cannabinus and H. indicum (leaf). C. carandas, H. cannabinus and H. indicum showed significant IC50 value in protein denaturation.