In-vitro Evaluation of Antioxidant and Photoprotective Activity of Sida cardifolia and Abutilon indicum

Abstract

Excess of Free radicals leads to accumulation in body which results in oxidative stress. Accumulation of free radicals results in diseases like cancer, arthritis, skin diseases, autoimmune disorders, aging, cataract, rheumatoid arthritis, cardiovascular and neurodegenerative diseases. Antioxidants play crucial role in the management of such diseases. Polyphenolic constituents of plants are the good source of antioxidant, can be use in the treatment and management of many diseases. The aim of present study invitro evaluation of antioxidant and photoprotective activity of the alcoholic, hydroalcoholic and aquous extracts of S. cardifolia and A. indicum. Aquous, hydroalcholic and alcoholic extract of S. cardifolia and A. indicum were prepared and evaluated for total phenolic content by Folin-ciocaltechu method, antioxidant activity by DPPH method and photoprotective effect by UV spectrophotometer method. Results showed that hydroalcoholic extracts of S. cardifolia and A. indicum showed highest phenolic content, while hydroalcoholic extract of S. cardifolia and water extract of A. indicum showed potent antioxidant activity, while hydroalcoholic extract of S. cardifolia and A. indicum showed maximum photoprotective effect as compared to alcoholic and water extract. Hydroalcoholic extracts of S. cardifolia and A. indicum showed highest phenolic content, potent antioxidant activity and maximum photoprotective effect. The result revealed that S. cardifolia and A. indicum possess potent antioxidant and photoprotectve effect, which can be use in the management of various diseases and as a photo protective in skin diseases.