Abstract
Antioxidants are vital substances that have an ability to protect the body from various damages caused by free radical-induced oxidative stress. Plants are the source of a wide variety of natural free radical scavenging antioxidants. The objective of the present study is to carry out in vitro antioxidant tests to evaluate the antioxidant ability of Methanolic extracts of selected mangrove plans i.e., Aegiceras corniculatum, Excoecaria agallocha and Lumnitzera racemosa. In this study, In vitro antioxidant activity was estimated by assays like DPPH, Reducing power assay and total antioxidant activity methods. The in vitro antioxidant studies revealed that, the extract of Lumnitzera racemosa has the highest phenolic content (38.80 ± 0.19 µg GAE/ 100 µg) and highest antioxidant potential. This is followed by Aegiceras corniculatum (24.06 ± 0.79 µg GAE/100 µg) and, Excoecaria agallocha (20.56 ± 0.58 µg GAE/100 µ). This study provides the preliminary data that can pave the way for further studies to validatee their medicinal uses and focus on bioassay guided fractionation and isolation of active compounds from the extracts.
Highlights
Free radicals are highly reactive molecules that contain one or more unpaired electrons
% of Inhibition threatening diseases. Keeping this in mind we have attempted to make a study on antioxidant potentials of selected mangrove plants
In order to characterize and analyze antioxidant activity of plant extracts, it is desirable to subject the extracts for the tests that evaluate the range of activities such as scavenging of the free radicals or reactive oxygen species, inhibition of membrane LPO and metal ion chelation
Summary
Free radicals are highly reactive molecules that contain one or more unpaired electrons. They either donate or take electrons from other molecules in an attempt to pair with their electrons and generate more stable species. Reactive oxygen species generated in the organism are usually removed or neutralized by an efficient network of defense mechanism in the body. When the formation of these free radicals or reactive oxygen species exceeds the levels of defensing mechanism, it leads to the damage of tissues, bio molecules and further, leading to disease conditions especially degenerative diseases such as Aging, Diabetes, Arthritis, Carcinogenesis, and Cardio Vascular diseases [3,4,5,6]
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