Abstract

Assessment of cytotoxicity, antibacterial activity and phytochemical screening of ethanol extract of Phyllanthus acidus L. (family: Euphorbiacceae) BarkSubrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Kumar Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan

Highlights

  • Aceh has several geothermal sites which are contributed by volcanic activities from Jaboi (Idroes et al, 2021b), Seulawah Agam (Marwan et al, 2019a, 2019b), and Burni Geureudong (Dharma et al, 2021; Marwan et al, 2021; Putri et al, 2019)

  • Antibacterial activity testing revealed that the higher the ethanolic Calotropis gigantea leaf extract (ECGLE) concentration, the more effective it is against bacteria

  • Stability tests conducted on the mouthwash formulation using organoleptic, temperature, viscosity, and pH parameters (Table 2) revealed that formulation 3 (F3) performed significantly better than the other formulations

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Summary

Introduction

Aceh has several geothermal sites which are contributed by volcanic activities from Jaboi (Idroes et al, 2021b), Seulawah Agam (Marwan et al, 2019a, 2019b), and Burni Geureudong (Dharma et al, 2021; Marwan et al, 2021; Putri et al, 2019). Calotropis gigantea, from the family Asclepiadaceae, is a unique plant from Southeast Asia. This plant is known as giant milkweed/swallow-wort (English), erukku (Indian), remiga (Malaysian), and widuri or biduri (Indonesian), and in Aceh, it is known as rubeek (Sampath Kumar et al, 2015)

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