Abstract

Assessment of cytotoxicity, antibacterial activity and phytochemical screening of ethanol extract of Phyllanthus acidus L. (family: Euphorbiacceae) BarkSubrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Kumar Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan

Highlights

  • Zanthoxylum alatum Roxb. (Family: Rutaceae) is an evergreen plant of the Himalayan regions in India commonly known as Tejphal (Hindi) and Timur (Nepal) (Tiwary et al, 2007; Singh and Singh, 2011).Nepalese traditionally used the fruit decoction in abdominal pain, bark extract as cholera, diabetes and asthma

  • The present study evaluates the antioxidant and cytotoxic activity of Zanthonitrile isolated from Zanthoxylum alatum leaves

  • An amorphous powder was found by eluted the solvent hexane: ethyleacetate (85:15) and characterized by ultra violet– visible (UV–vis), infrared spectroscopy (IR), mass spectrometry and proton and carbon-13 nuclear magnetic resonance (NMR)

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Summary

Introduction

Nepalese traditionally used the fruit decoction in abdominal pain, bark extract as cholera, diabetes and asthma. The plant is used for the treatment of fever, dyspepsia, cholera, anthelmintic, general debility (Jain et al, 2001; Kalia et al, 1999). It has been proven that the plant have the antibacterial, antifungal, anthelmintic and larvicidal activities (Tiwary et al, 2007). As well as hepatoprotective (Ranawat et al, 2010), antinociceptive, anti-inflammatory (Guo et al, 2011), antipyretic activities, antioxidant and antimicrobial activities have been proven (Karmakar et al, 2015a). The aim of the present study was structure elucidation of the isolate and its antioxidant and cytotoxic activity

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