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Abstract
The growing issue of clinical obesity has led to increased consumption of weight-loss dietary supplements containing hydroxycitric acid (HCA) derived from the fruit rind of Garcinia cambogia, a plant widely distributed in Asia and Africa. It is often consumed in an unregulated manner, beyond the permissible dose, to achieve the target weight-loss. However, its safety/efficacy is controversial and reports on cytotoxicity and genotoxicity are limited and inconsistent. Hence, we aimed to study the putative effects of HCA on genotoxicity in human peripheral blood cells.
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