Abstract
Objective To replicate experimental animal model of knee osteoarthritis and to investigate the method of culture and biological characteristics of rats synoviocytes of gonarthritis in vitro. Methods Animal models of knee osteoarthritis were made by the Modified Hulth method. 4 weeks after the replicating experiment, synovial tissues were mechanically isolated and enzyme-digested and the growth of the synovial ceils was investigated. Results The synovial tissues were obviously hyperplasia in the model made by the Modified Huhh method. The synovial cells were abundant after enzyme-digested cultivation and the cell activity was higher than 98%. Conclusion The study exhibits that the Modified Hulth method apparently promotes the hyperplasia of synovial tissues. The methods of isolation and cultivation of the synovial eells in vitro is proved to be simple and feasible. Key words: Osteoarthritis; Synovial cell; Cultivate
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
