In vitro Antioxydant Potential of Two Formulated Antidiabetic Powders by Using Nutraceutic Plants of Cameroon.

Abstract

Many modes of action have been explored in the fight against type 2 diabetes, including the use of drugs. But these drugs, in addition to their relatively high cost, are not without side effects. As an alternative to these difficulties, traditional pharmacopoeia use several nutraceutic plants in the treatment of type 2 diabetes including: Vernonia amygdalina, Tetrapleura tetraptera, Leptadenia lancifolia decne and Gum Arabic (Acacia Senegal sap). The fact that these plants are used for the same treatment means that they contain bioactive contents, which can be different depending on the plant. For this reason production of formulated powders (JE1 and JE2) of these plants with good anti-diabetic effects can help in the treatment of some chronic diseases. To assess the efficacy of the formulated powders a study of antioxidant activity of two formulated powders was evaluated. Formulation of powders and comparative analyses of bioactive compounds of different formulated powders obtained was done by using classical methods. The results revealed some difference in the phytochemical contents of the both formulated powders. JE1 is rich in mineral and anti-nutrition contents and JE2 is rich in vitamin C. JE1 and JE2 possess strong antiradical activities, but in general JE1 has the better free radical scavenging efficacy and antiradical activity compared to JE2. Indeed the results reveal that JE1 and JE2 can have an impact on the control of oxidative stress on patients suffering from type 2 diabetes and this explains why Vernonia amygdalina, Tetrapleura tetraptera, Leptadenia lancifolia decne and Gum Arabic (Acacia Senegal sap) are used in the traditional pharmacopoeia for treatment of type 2 diabetes. For this reason consumption of these plants need to be encouraged.