Abstract
In vitro anti-malarial activity of petroleum ether extracts of Ficus sycomorus leaves was investigated using Candle Jar method. The extractions were carried out through activity guided fractionation. Petroleum ether extract has the highest activity, at the concentration of 1mg and 0.5mg with percentage growth inhibition of (33.12 and 31.9%) respectively. These results suggest that the leaves of Ficus sycomorus plant have significant antimalarial activity and that the antiplasmodial agents might be as a result of the extract fractionated using the petroleum.
Highlights
Malaria is a mosquito-borne infections disease caused by a eukaryotic protest of the genus plasmodium
The results of extraction of leaves of Ficus Sycomorus obtained through activity guided fractionation are shown above (Table 3.1) with yield and percentage yield of plant material of petroleum ether
In this study four organic extract were obtained from a plant (Ficus sycomorus leaves) that are used for the treatment of fever and malaria were tested In vitro against P. falciparum using Candle Jar Method
Summary
Malaria is a mosquito-borne infections disease caused by a eukaryotic protest of the genus plasmodium. It is wide spread in tropical and subtropical regions, including parts of the American, Asia and Africa. When a mosquito bites an infected person, a small amount of blood is taken, which contains malaria parasites. These develop within the mosquito and about one week later, when the mosquito takes the blood meal, the parasites are injected with the mosquito’s saliva in to the person being bitten. Many countries are under developed, the challenge of producing a widely available vaccine that provides a high level of protection for a sustained period is still to be met
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