Abstract
Many plants of Cordia genus are ethanomedically used to treat various diseased conditions like urine infection, leprosy, lung diseases and act as anti-inflammatory, anthelmintic, appetitie suppressant, cough suppressant, diuretic and antimalarial agents. Cordia myxa is one of that traditionally important plants. The aim of the present research is to investigate the chemical composition, antioxidant, anti-arthritic and anti-inflammatory effects of aqueous and ethanolic extracts of Cordia myxa leaves. Phytochemical investigation indicates the presence of alkaloids, phenols, flavanoids etc. responsible for tremendous pharmacological activities. Both the extracts were found to express significant free radical scavenging activity in dose dependent manner with highest 67.87% by aqueous extract. In vitro antiinflammatory and anti-arthritic were also determined where aqueous extract showed maximum inhibition in HRBC membrane lyses with 68.73% inhibition and 72.4% inhibition in protein denaturation which confers potential anti-arthritic activity.
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