Abstract
In-stent neoatherosclerosis after DES implantation including neointima-calcification is reported (JACC2011; 57). The long-term neointimal features of patients undergoing hemodialysis (HD) remain unknown. Methods: We assessed neointima-calcification in 31 HD patients and 201 control patients after DES/BMS implantation over extended late phase (> 5 years) by serial IVUS analysis. (Figure: Neointima-calcification obtained by atherectomy invivo) Results: The incidence of neointima-calcification was significantly higher in HD-group (58.1%) than non-HD (13.9%; p<0.0001). The median stent duration with neointima-calcification was significantly shorter in HD (0.81 yrs) than non-HD (7.6 yrs; p<0.0001). In HD-group, the prevalence of neointima-calcification was similar between DES and BMS (62.5% vs 56.5%, p=ns). Neointima-calcification in vivo Conclusions: Neointima within both DES and BMS transforms into neointima-calcification frequently and earlier in patients with hemodialysis than without, which may cause unfavorable outcome after stenting for hemodialysis patients.
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