Abstract
T-killer cells of the immune system eliminate virus-infected and tumorous cells through direct cell to cell interactions. Reorientation of the killing apparatus inside the T-killer cell to the interface with the target cell ensures specificity of the immune response. Several research works were reported to explain the mechanism of reorientation but the most adversary situation, when the cell's initial orientation is complete opposite to the desirable direction, always left skepticism toward the suggested mechanism.
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