In silico, in vitro, and in vivo validation of a microwave imaging system using a low‐profile Ultra Wide Band Archimedean spiral antenna to detect skin cancer

Abstract

AbstractMicrowave imaging (MI) is a noninvasive and nonionizing procedure for detection of cancerous cells in healthy body tissues using radiofrequency (RF) and microwaves. The procedure involves the use of Ultra Wide Band (UWB) antennas for sensing purposes. Therefore, this research article presents the design, development, and testing of a low‐profile UWB Archimedean spiral microstrip‐patch antenna (ASMA) for detection of skin cancer using monostatic radar‐based microwave imaging. The proposed ASMA consists of a spiral resonator with a defective ground structure and a slotted microstrip feed line with dimensions of 38 × 38 × 0.87 mm3. The proposed antenna shows an impedance bandwidth for the frequency range of 2.2–13.9 GHz, with a peak gain of 6.8 dB at 7.8 GHz. In silico analysis of the proposed ASMA for MI is carried out with Gaustav model using Computer Simulation Technology Microwave Studio. To validate the performance of the ASMA as a sensor for MI, a prototype of the same is fabricated and a four‐layered bio‐phantom of the human forearm is prepared for in vitro and in vivo testing of the proposed procedure. The validation of ASMA radiation properties is done using a Vector Network Analyser (E‐5063A) (VNA) and an anechoic chamber with the fabricated antenna at 10 mm away from the prepared bio‐phantom. The recorded S parameter data with bio‐phantom and the VNA is processed using different beamforming algorithms like Delay and Sum and Coherent Factor‐Delay Multiply and Sum (CF‐DMAS) to reconstruct the image of the scanned area. The reconstructed images are 97%–98% accurate. The proposed ASMA sensor is also safe for human exposure as it has a specific absorption rate of 0.0546 W/Kg at 5 GHz that complies with the safety guidelines of the Federal Communications Commission to minimize potential health risks associated with exposure to RF and microwave radiation.