Abstract
Background : The benefit of PCI to improve quality of life (QoL) in chronic coronary syndrome (CCS) is still unclear. Objectives : This study aimed to assess the benefit of percutaneous coronary intervention (PCI) in improving QoL among CCS patients receiving OMT. Methods : We conducted a retrospective cohort study. CCS patients who underwent coronary angiography (CAG) and/or PCI were grouped into OMT plus PCI and OMT groups. The SYNTAX score was used to assess the complexity and severity of coronary artery lesions. The outcome measured was QoL assessed using Seattle Angina Questionnaire (SAQ) and rehospitalization. Results: A total of 57 patients in the OMT plus PCI group and 49 patients in the OMT group were included. The percentage of patients with good QoL was higher in the OMT plus PCI group than OMT only group (64.5% vs. 35.5%; p = 0.007). The OMT plus PCI group revealed a better activities of daily living (85.11 ± 12.46 vs. 12.46 ± 21.87; p = 0.014) and angina stability (84.32 ± 23.63 vs. 71.81 ± 27.89; p = 0.014) than OMT group. Among patients with SYNTAX scores of more than 22, achievement of good QoL was greater in the OMT plus PCI group than the OMT group (80.8% vs. 45.5%; p = 0.025). Conclusion: PCI improved the QoL in CCS patients treated with OMT. Second, OMT plus PCI improves physical limitation and angina stability. For patients with a SYNTAX score of more than 22, OMT plus PCI was correlated with good QoL achievement.
Highlights
Coronary artery disease (CAD) is a disease characterized by atherosclerotic plaque formation in the epicardial coronary arteries.[1,2] It is well known as the leading cause of mortality around the world.[2,3] Annually, in Indonesia, at least 470,000 mortalities are estimated to be caused by CAD or stroke.[4]
Among patients with Synergy Between PCI With Taxus and CABG (SYNTAX) scores of more than 22, achievement of good quality of life (QoL) was greater in the optimal medical treatment (OMT) plus percutaneous coronary intervention (PCI) group than the OMT group (80.8% vs. 45.5%; p = 0.025)
PCI improved the QoL in chronic coronary syndrome (CCS) patients treated with OMT
Summary
Coronary artery disease (CAD) is a disease characterized by atherosclerotic plaque formation in the epicardial coronary arteries.[1,2] It is well known as the leading cause of mortality around the world.[2,3] Annually, in Indonesia, at least 470,000 mortalities are estimated to be caused by CAD or stroke.[4]. The CCS is defined as the progressive atherosclerotic plaque accumulation process accompanied by functional alteration in the coronary artery. It has replaced the old terminology stable CAD.[1] The management of CCS includes lifestyle changes, optimal medical treatment (OMT), and myocardial revascularization.[1,5]. Objectives : This study aimed to assess the benefit of percutaneous coronary intervention (PCI) in improving QoL among CCS patients receiving OMT. Among patients with SYNTAX scores of more than 22, achievement of good QoL was greater in the OMT plus PCI group than the OMT group (80.8% vs 45.5%; p = 0.025). For patients with a SYNTAX score of more than 22, OMT plus PCI was correlated with good QoL achievement
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call