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Abstract
Background: Although primary percutaneous coronary intervention is the recommended method of reperfusion for ST-segment elevation myocardial infarction patients, thrombolytic therapy should still be given to ST-segment elevation myocardial infarction patients when anticipated delay in percutaneous coronary intervention is more than 120 minutes from first medical contact.
 Objective: The aim of this study is to assess improvement of door to needle time in cases of ST-segment elevation myocardial infarction after applying new clinical pathway for cases of ST-segment elevation myocardial infarction presenting to Emergency Department at King Abdulaziz University Hospital over one year period.
 Methods: A prospective study conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, in patients with ST-segment elevation myocardial infarction who underwent thrombolysis from November 2012 to October 2013 to compare door to needle time obtained from this study with door to needle time from previous records during October 2010 till September 2011.
 Results: A total of 93 patients with ST-segment elevation myocardial infarction received thrombolytic in Emergency Department. Mean age 50 years. Median door to Electrocardiogram 3 minutes, median Electrocardiogram to thrombolytic 25 minutes and door to needle time 30 minutes. 54.8% of patients received thrombolytic within 30 minutes or less.
 Conclusions: Improvement in door to needle time for thrombolysis of cases of ST-segment elevation myocardial infarction has been achieved at King Abdulaziz University Hospital during the period of the study compared to previous data.
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