Abstract
Improved SPECT reconstructions have been obtained by the use of an Inverse Monte Carlo (IMOC) reconstruction algorithm. Monte Carlo solution to the photon transport equation for SPECT generates an accurate system response model for use in an iterative Maximum Likelihood estimation (MLE) algorithm. Reconstruction from simulated projections demonstrate that the MLE algorithm continues to converge at 1000 iterations for noise free data. Reconstruction from experimentally acquired projections reveals superior RMS noise and resolution recovery when compared with filtered backprojection for simple phantoms. Compensation for scatter and attenuation is provided by including these effects in the Monte Carlo simulation.
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