Abstract
Lung cancer is the second most common form of cancer in both men and women. It is responsible for at least 25% of all cancer-related deaths in the United States alone. Accurate and early diagnosis of this form of cancer can increase the rate of survival. Computed tomography (CT) imaging is one of the most accurate techniques for diagnosing the disease. In order to improve the classification accuracy of pulmonary lesions indicating lung cancer, this paper presents an improved method for training a densely connected convolutional network (DenseNet). The optimized setting ensures that code prediction error and reconstruction error within hidden layers are simultaneously minimized. To achieve this and improve the classification accuracy of the DenseNet, we propose an improved predictive sparse decomposition (PSD) approach for extracting sparse features from the medical images. The sparse decomposition is achieved by using a linear combination of basis functions over the L2 norm. The effect of dropout and hidden layer expansion on the classification accuracy of the DenseNet is also investigated. CT scans of human lung samples are obtained from The Cancer Imaging Archive (TCIA) hosted by the University of Arkansas for Medical Sciences (UAMS). The proposed method outperforms seven other neural network architectures and machine learning algorithms with a classification accuracy of 95%.
Highlights
The lung is a large organ, and this means that tumors can keep growing for a long time before being detected
This paper aims to present an improved method of sparse representation of the input data matrix for lung cancer prediction implemented with a recently proposed Convolutional neural networks (CNNs) architecture called densely connected convolutional network (DenseNet)
This paper proposes the use of the improved predictive sparse decomposition (PSD) approach with DenseNet to remedy the above-mentioned problems
Summary
The lung is a large organ, and this means that tumors can keep growing for a long time before being detected. With advancements in computing techniques and artificial intelligence, it is possible to minimize the problem of lung cancer misdiagnosis due to inaccurate interpretation of lung CT images. This is because differences between cancerous and non-cancerous lesions are generally not easy to detect [2]. An optimal sparse representation of image data matrices is a vital requirement for accurate approximation of the input matrix into the classifier. It is essential in denoising of matrices representing image data since it attempts to capture crucial details of the image matrix with the least possible number of features. Sparse representation aims to make prediction of the regressor as close as possible to the optimal set of coefficients R∗ represented by Eq (1): Γ(Φ, R; F)
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