Abstract
The quartet method is a novel hierarchical clustering approach where, given a set of n data objects and their pairwise dissimilarities, the aim is to construct an optimal tree from the total number of possible combinations of quartet topologies on n, where optimality means that the sum of the dissimilarities of the embedded (or consistent) quartet topologies is minimal. This corresponds to an NP-hard combinatorial optimization problem, also referred to as minimum quartet tree cost (MQTC) problem. We provide details and formulation of this challenging problem, and propose a basic greedy heuristic that is characterized by some appealing insights and findings for speeding up and simplifying the processes of solution generation and evaluation, such as the use of adjacency-like matrices to represent the topology structures of candidate solutions; fast calculation of coefficients and weights of the solution matrices; shortcuts in the enumeration of all solution permutations for a given configuration; and an iterative distance matrix reduction procedure, which greedily merges together highly connected objects which may bring lower values of the quartet cost function in a given partial solution. It will be shown that this basic greedy heuristic is able to improve consistently the performance of popular quartet clustering algorithms in the literature, namely a reduced variable neighbourhood search and a simulated annealing metaheuristic, producing novel efficient solution approaches to the MQTC problem.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.